Genotype 1 and Hepatitis C Treatment

The most common form of hepatitis C virus in the United States is genotype 1. About 50 percent of people with genotype 1 have a successful response to treatment with peginterferon and ribavirin. Other factors, such as the amount of virus in the body and other coexisting medical conditions, can also influence how well a person responds to hepatitis C treatment.

 

How Genotype 1 Affects Hepatitis C Treatment

If you are infected with genotype 1 of the
 hepatitis C virus (HCV), there are a few things you should know about the treatment for hepatitis C.
 
Genotype 1 is the most common form of HCV in the United States. It affects over 70 to 90 percent of the people in this country who have hepatitis C. It is estimated that up to 50 percent of the people with genotype 1 will have a sustained response (successful treatment) with peginterferon and ribavirin.
 
There are other factors that can also affect your chances of having a successful treatment, including:
 
  • The amount of virus in your body (see Hepatitis C Viral Load)
  • How long you have had hepatitis C
  • How much liver damage has already occurred
  • Any other medical conditions you may have.
     
Since hepatitis C can affect people in different ways, be sure to discuss your individual situation with your healthcare provider.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;