If you've been losing weight as you take combination therapy for hepatitis C, there are a few things you can try. First, try eating 4 to 6 smaller meals throughout the day instead of having 1 or 2 big meals. Also, consider buying an instant breakfast mix. You can mix it with milk or juice, or make yourself a fruit smoothie. Another alternative is to use a canned nutritional supplement drink, like Ensure^®. The instant breakfast mix or the canned drink can be taken in between your lunch and dinner meals.