Hepatitis C

Hepatitis C is a disease that causes inflammation of the liver. It is caused by infection with the hepatitis C virus (HCV), which is spread most frequently when a person comes in contact with infected blood. Approximately 300 million people worldwide are infected with the hepatitis C virus, and 3.9 million people in the United States have chronic hepatitis C. Treatment for hepatitis C, when recommended, often involves two medications: peginterferon and ribavirin.

 

What Is Hepatitis C?

Hepatitis C is an inflammation of the liver. While different things can cause other types of hepatitis, a specific virus -- the hepatitis C virus -- causes hepatitis C. This virus is also known as HCV.
 

Acute Versus Chronic Hepatitis C

There are two types of hepatitis C: acute and chronic. In acute hepatitis C, the body is able to completely kill the hepatitis C virus. This happens in about 15 percent of people infected with the hepatitis C virus. In about 85 percent of people infected with HCV, the body is not able to completely get rid of the virus and they end up having a long-term liver infection. This is called chronic hepatitis C.
 

Hepatitis C Genotypes

Just as there are different types of hepatitis viruses, there are also a few different types of the hepatitis C virus itself.
 These are known as hepatitis C genotypes. The main hepatitis C genotypes are known simply as: genotypes 1, 2, 3, 4, 5, and 6. The genotype is important to know because some genotypes are harder to treat than others.
 
(The eMedTV article Following Your Hepatitis C Treatment Program explains why knowing the specific genotype of the hepatitis C virus is important.)
 
Of the different hepatitis C genotypes, genotype 1 is the type most commonly found in the United States. Between 70 and 90 percent of Americans with hepatitis C have this genotype. Hepatitis C genotypes 2 and 3 are less common. Only 10 to 20 percent of infected people in this country have either of these genotypes.
 
(Hepatitis C Continued: Page 2)
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD