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INCIVEK Drug Interactions

Phosphodiesterase Type-5 (PDE5) Inhibitors
Taking INCIVEK with a PDE5 inhibitor may increase the level of the PDE5 inhibitor in your bloodstream, potentially increasing your risk for side effects. Talk to your healthcare provider before taking these medications together. INCIVEK should never be combined with sildenafil or tadalafil when these medications are used to treat pulmonary arterial hypertension.
 
Pimozide
INCIVEK and pimozide should never be combined, due to the increased risk of a dangerous irregular heart rhythm (arrhythmia).
  
Protease Inhibitors
Combining INCIVEK with other protease inhibitors can decrease blood levels of INCIVEK, while having varying effects on blood levels of the other protease inhibitors. For this reason, it is recommended that these medicines not be used together.
 
Repaglinide
INCIVEK may increase the level of repaglinide in the bloodstream, perhaps increasing the risk for side effects. Check with your healthcare provider before combining these medications.
 
Rifabutin
Rifabutin can decrease levels of INCIVEK in your bloodstream, potentially making it less effective. INCIVEK may increase blood levels of rifabutin, potentially increasing your risk for side effects. It is recommended that these medicines not be used together.
 
Salmeterol
INCIVEK may increase blood levels of salmeterol, possibly increasing your risk for potentially serious side effects, including heart rhythm problems. You should not take salmeterol with INCIVEK.
 
Trazodone
Taking INCIVEK with trazodone could increase the level of trazodone in your bloodstream, potentially increasing your risk for side effects, such as nausea, dizziness, and low blood pressure. Your healthcare provider may need to give you a lower trazodone dose during INCIVEK treatment.

INCIVEK Drug Information

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