Hepatitis C Home > INCIVEK

Available by prescription only, INCIVEK is used to treat chronic hepatitis C infections. It comes in the form of a tablet and is taken by mouth two times a day for 12 weeks. This medicine works by blocking the action of certain enzymes in the body, which prevents the hepatitis C virus from reproducing. Side effects may include nausea, vomiting, and diarrhea.


INCIVEK® (telaprevir) is a prescription medication approved to treat chronic hepatitis C infections. It is always used in combination with two other hepatitis C medications: peginterferon alfa (Pegasys®, PEG-Intron®) and ribavirin (Copegus®, Rebetol®, RibaPak®, Ribasphere®). INCIVEK is only approved for use in people who have stable liver problems and have not been treated before or have failed previous treatment.
(Click INCIVEK Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

INCIVEK is made by Vertex Pharmaceuticals Incorporated.

How Does INCIVEK Work?

INCIVEK belongs to a group of medications called protease inhibitors. It works by inhibiting the activity of enzymes called proteases. Protease enzymes are used by the hepatitis C virus to clip long protein strands into shorter, usable strands. The virus then uses these shorter strands to replicate itself (reproduce). By blocking the protease enzyme, INCIVEK prevents the hepatitis C virus from reproducing.
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Last reviewed by: Kristi Monson, PharmD;
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