Hepatitis C Home > Sovaldi Warnings and Precautions

By discussing your medical history and current medications with your healthcare provider before starting treatment with Sovaldi, you can help reduce your risk of complications. There are many safety precautions for Sovaldi, including warnings of potential drug interactions and allergic reactions. Also, women who are pregnant or men who have a partner who is pregnant should not use this medicine.

 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Sovaldi™ (sofosbuvir) if you have:
   
Also, let your healthcare provider know if you are:
 
  • Pregnant, thinking of becoming pregnant, or have a female partner who is pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Sovaldi

Some warnings and precautions to be aware of prior to taking this drug include the following:
 
  • Sovaldi has not been studied in people with "decompensated" cirrhosis of the liver, although it has been studied in people with liver cancer awaiting liver transplantation, as well as in people in all stages of liver failure.
 
  • Sovaldi can interact with a number of other medications. Some medications should not be used in combination with Sovaldi (see Sovaldi Drug Interactions).
 
  • Sovaldi is a pregnancy Category B medication, which usually means a drug is fairly safe for use during pregnancy. However, Sovaldi is always used in combination with ribavirin, which is a pregnancy Category X medication. Therefore, Sovaldi should not be used in pregnant women, or in men whose partner is pregnant. Women must use two forms of birth control during treatment (see Sovaldi and Pregnancy).
 
  • It is unknown if Sovaldi passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Sovaldi and Breastfeeding).
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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