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Preparing the Medicine (Peg-Intron)

Clip Number: 14 of 16
Presentation: Peg-Intron Combination Therapy
The following reviewers and/or references were utilized in the creation of this video:
Reviewed By: Arthur Schoenstadt, MD
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To prepare the medicine, first, make sure that the expiration date on the vial has not passed. If it has, call your pharmacist or healthcare provider. Remove the protective caps from each of the vials. A rubber stopper on each of the vials will become exposed. Clean the rubber top of each vial with an alcohol swab.
Then remove the protective cap from the end of the syringe. Turn the syringe so the needle is pointing up and pull the plunger back exactly to the 0.7 milliliters mark on the syringe. Then insert the needle into the sterile water vial and press the plunger back to 0 milliliters. This will remove the air from the syringe and put it into the vial. With the needle inserted, turn the vial upside down and remove exactly 0.7 milliliters of the liquid by pulling the plunger back on the syringe. Remove the needle from the vial. Make sure to throw the vial away. Do not use it again even if there is liquid remaining.
Now it is time to make the powder medicine into a liquid. Take the syringe with the sterile water, insert it through the rubber top of the vial containing the powder and place the needle tip against the glass of the vial. Slowly inject the sterile water into the powder. Do not aim the water directly at the powder because this can cause problems with the medicine.
After the sterile water has been injected into the powder, remove the empty syringe and swirl the vial in a gentle circular motion until the powder is completely dissolved. The liquid should now be clear, colorless and without particles. If it is does not look right, call your healthcare provider or pharmacist. If the solution is cold, you can warm it up by gently rolling it between your hands. If air bubbles form, wait for them to rise to the top before you take out the medicine.
After the medicine is completely dissolved take the second syringe and repeat the same steps for when you removed the sterile water. First make sure to clean the rubber top with an alcohol swab. Then turn the syringe so the needle is facing upwards, fill the syringe with air to the proper medicine level, push the air into the vial, turn the syringe and vial upside down, fill the syringe with the proper amount of medicine then remove the needle. If there are any air bubbles in the syringe after it is removed from the vial, gently tap the syringe until all the air bubbles are at the top. Then slowly push the plunger in just enough to remove the air bubbles. Now you are ready to inject the medicine.
 

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