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VICTRELIS Drug Interactions

Certain Calcium Channel Blockers
VICTRELIS may increase blood levels of certain calcium channel blockers, possibly increasing your risk for side effects. Your healthcare provider may choose to monitor you more closely if you take these medicines together and adjust your calcium blocker dosage if needed.
Certain Corticosteroids
Dexamethasone can decrease blood levels of VICTRELIS, potentially making it less effective. Blood levels of certain other corticosteroids (inhaled budesonide and fluticasone) can be increased in the body when combined with VICTRELIS. If possible, VICTRELIS should not be used with dexamethasone or inhaled budesonide or fluticasone.
Certain Immunosuppressants
VICTRELIS can increase blood levels of cyclosporine, tacrolimus, and sirolimus, possibly increasing the risk for side effects. If you take these drugs together, your healthcare provider will need to monitor you more closely for potential side effects. Your healthcare provider will check your blood levels of your immunosuppressant and decrease your dose as necessary.
Certain Statin Medications
VICTRELIS can increase the blood levels of certain statin medications, potentially increasing your risk for side effects, including statin-related muscle problems. You should not take lovastatin or simvastatin while taking VICTRELIS. In addition, the atorvastatin dosage should not exceed 20 mg a day when used with VICTRELIS. If you have high cholesterol, your healthcare provider may choose to give you a different statin during VICTRELIS treatment.
VICTRELIS increases colchicine blood levels, increasing your risk for potentially serious side effects. People with kidney and liver disease other than hepatitis C should not take these drugs together. If they are taken together, a lower colchicine dosage should be used.

VICTRELIS Drug Information

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