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VICTRELIS Warnings and Precautions

If you have anemia, liver disease, or a weakened immune system, talk to your healthcare provider before using VICTRELIS. This medication can cause blood cell problems (such as anemia), so your blood will be checked periodically during treatment to ensure this drug is still suitable. Other warnings and precautions for VICTRELIS extend to people with certain allergies and women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking VICTRELIS™ (boceprevir) if you have:
 
  • Blood cell problems, such as anemia
  • A weakened immune system due to human immunodeficiency virus (HIV), acquired immunodeficiency syndrome (AIDS), or any other cause
  • Liver disease other than hepatitis C, such as hepatitis B, cirrhosis, or liver failure
  • Ever had an organ transplant
  • Plans to have surgery
  • Any allergies, including to foods, dyes, or preservatives.
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Also, let your healthcare provider know if you are:
 
  • Pregnant, thinking of becoming pregnant, or have a female partner who is pregnant
  • Breastfeeding.
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Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings With VICTRELIS

Some warnings and precautions to be aware of prior to taking this drug include the following:
 
  • VICTRELIS is only approved for use in combination with peginterferon alfa (Pegasys®, PEG-Intron®) and ribavirin (Copegus®, Rebetol®, Ribapak®, Ribasphere®). If you cannot take peginterferon alfa or ribavirin, you cannot take VICTRELIS.
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  • VICTRELIS can cause blood cell problems, including anemia (low red blood cells) and neutropenia (low white blood cells). Your healthcare provider will do periodic blood tests during treatment to monitor you for these side effects. If you develop severe anemia, your healthcare provider may reduce the dose of ribavirin. If you continue to have severe anemia, your healthcare provider may tell you to stop taking VICTRELIS.
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  • Your healthcare provider will perform regular blood tests while you take this medication to make sure it is working and to check for potentially serious side effects. Be sure to keep all your healthcare appointments.
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  • VICTRELIS can react with a number of other medications. Some products should not be used in combination with VICTRELIS (see VICTRELIS Drug Interactions).
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  • VICTRELIS is considered a pregnancy Category B medication; however, it is always used in combination with ribavirin, which is a pregnancy Category X medication. Therefore, VICTRELIS should not be used in pregnant women, or in men whose partner is pregnant. Women must use two forms of birth control during treatment (see VICTRELIS and Pregnancy).
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  • It is unknown if VICTRELIS passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see VICTRELIS and Breastfeeding).
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VICTRELIS Drug Information

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